Institut de Neurosciences Cognitives et Intégratives d'Aquitaine (UMR5287)

Aquitaine Institute for Cognitive and Integrative Neuroscience



INCIA - UMR 5287- CNRS
Université de Bordeaux

Zone nord Bat 2 2ème étage
146, rue Léo Saignat
33076 Bordeaux cedex
France

Téléphone 05.57.57.15.51
Télécopie 05.56.90.14.21

Supervisory authorities

CNRS Ecole Pratique des Hautes Etudes Université de Bordeaux

Our partners

Neurocampus Unitéde Formation de Biologie

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Masmejean Frédérique

by Loïc Grattier - published on , updated on

IE, CNRS

Contact:
frederique.masmejean@u-bordeaux.fr

Team:
Translational Research in Neurogenetic Diseases
Imagerie Moléculaire Translationnelle (IMT)

Research axis:

Previous Projects

  • Study of GABAa receptors expression (M. Garret)
  • Study on the cell regeneration properties of the salamander (Collaboration with JM Cabelgen and JR Cazalets)

Technical expertise:

  • Primary cells & organotypic cultures
  • Immunochemistry
  • Biochemistry
  • Fluo-microscopy

Selected publications:

  • Du Z, Tertrais M, Courtand G, Leste-Lasserre T, Cardoit L, Masmejean F, Halgand C, Cho YH and Garret M (2017) Differential Alteration in Expression of Striatal GABAAR Subunits in Mouse Models of Huntington’s Disease. Front. Mol. Neurosci. 10:198. doi: 10.3389/fnmol.2017.00198
  • Milan L, Courtand G, Cardoit L, Masmejean F, Barriere G, Cazalets JR, Garret M, Bertrand SS (2015) Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and SOD1G93A Lumbar Motoneurons. PloS one 10:e0135525.
  • Nafia I, Re DB, Masmejean F, Melon C, Kachidian P, Kerkerian-Le Goff L, Nieoullon A, Had-Aissouni L.. Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction. J Neurochem. 2008 Apr;105(2):484-96. doi: 10.1111/j.1471-4159.2007.05146.x. Epub 2007 Nov 26.
  • Canas PT, Velly LJ, Labrande CN, Guillet BA, Sautou-Miranda V, Masmejean FM, Nieoullon AL, Gouin FM, Bruder NJ, Pisano PS. Sevoflurane protects rat mixed cerebrocortical neuronal-glial cell cultures against transient oxygen-glucose deprivation: involvement of glutamate uptake and reactive oxygen species. Anesthesiology. 2006 Nov;105(5):990-8. doi: 10.1097/00000542-200611000-00021.
  • Nieoullon A, Canolle B, Masmejean F, Guillet B, Pisano P, Lortet S. The neuronal excitatory amino acid transporter EAAC1/EAAT3: does it represent a major actor at the brain excitatory synapse? J Neurochem. 2006 Aug;98(4):1007-18. doi: 10.1111/j.1471-4159.2006.03978.x. Epub 2006 Jun 27.
  • Broccardo C, Nieoullon V, Amin R, Masmejean F, Carta S, Tassi S, Pophillat M, Rubartelli A, Pierres M, Rougon G, Nieoullon A, Chazal G, Chimini G. ABCA2 is a marker of neural progenitors and neuronal subsets in the adult rodent brain. J Neurochem. 2006 Apr;97(2):345-55. doi: 10.1111/j.1471-4159.2006.03714.x. Epub 2006 Mar 15.
  • Labrande C, Velly L, Canolle B, Guillet B, Masmejean F, Nieoullon A, Pisano P. Neuroprotective effects of tacrolimus (FK506) in a model of ischemic cortical cell cultures: role of glutamate uptake and FK506 binding protein 12 kDa. Neuroscience. 2006;137(1):231-9. doi: 10.1016/j.neuroscience.2005.08.080. Epub 2005 Nov 10.
  • Guillet BA, Velly LJ, Canolle B, Masmejean FM, Nieoullon AL, Pisano P. Differential regulation by protein kinases of activity and cell surface expression of glutamate transporters in neuron-enriched cultures. Neurochem Int. 2005 Mar;46(4):337-46. Epub 2005 Jan 13.
  • Canolle B, Masmejean F, Melon C, Nieoullon A, Pisano P, Lortet S. Glial soluble factors regulate the activity and expression of the neuronal glutamate transporter EAAC1: implication of cholesterol.J Neurochem. 2004 Mar;88(6):1521-32.
  • Velly LJ, Guillet BA, Masmejean FM, Nieoullon AL, Bruder NJ, Gouin FM, Pisano PM. Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: role of glutamate and its transporters. Anesthesiology. 2003 Aug;99(2):368-75.
  • Kourrich S, Masmejean F, Martin-Eauclaire MF, Soumireu-Mourat B, Mourre C. Inwardly rectifying Kir3.1 subunit knockdown impairs learning and memory in an olfactory associative task in rat. Brain Res Mol Brain Res. 2003 May 12;113(1-2):97-106.
  • Vacher H, Romi-Lebrun R, Crest M, Masmejean F, Bougis PE, Darbon H, Martin-Eauclaire MF. Functional consequences of deleting the two C-terminal residues of the scorpion toxin BmTX3. Biochim Biophys Acta. 2003 Mar 21;1646(1-2):152-6.
  • Guillet B, Lortet S, Masmejean F, Samuel D, Nieoullon A, Pisano P. Developmental expression and activity of high affinity glutamate transporters in rat cortical primary cultures. Neurochem Int. 2002 Jun;40(7):661-71.
  • Vacher H, Romi-Lebrun R, Mourre C, Lebrun B, Kourrich S, Masméjean F, Nakajima T, Legros C, Crest M, Bougis PE, Martin-Eauclaire MF. A new class of scorpion toxin binding sites related to an A-type K+ channel: pharmacological characterization and localization in rat brain. FEBS Lett. 2001 Jul 13;501(1):31-6.
  • Lortet S, Samuel D, Had-Aissouni L, Masmejean F, Kerkerian-Le Goff L, Pisano P. Effects of PKA and PKC modulators on high affinity glutamate uptake in primary neuronal cell cultures from rat cerebral cortex. Neuropharmacology. 1999 Mar;38(3):395-402.
  • Cupo A, Leger L, Charnay Y, Fourrier O, Jarry T, Masmejean F. The proenkephalin-A-derivative Met-enkephalin-Arg-Gly-Leu is not present in the feline species. Neuropeptides. 1990 Dec;17(4):171-6.
  • Glaser P, Ladant D, Sezer O, Pichot F, Ullmann A, Danchin A. The calmodulin-sensitive adenylate cyclase of Bordetella pertussis: cloning and expression in Escherichia coli. Mol Microbiol. 1988 Jan;2(1):19-30.
  • Mattei D, Pichot F, Bellalou J, Mercereau-Puijalon O, Ullmann A. Cloning of a coding sequence of "Bordetella pertussis" filamentous hemagglutinin gene. Ann Sclavo Collana Monogr. 1986;3(1-2):307-11. No abstract available.