Chargé de Recherches CNRS (CRCN), HDR
Contact:
mathieu.wolff@u-bordeaux.fr
+33 (0)5 57 57 95 07
Site : Charles Perrens
Team:
Decision and Adaptation
Social:
ResearchGate / Loop / LinkedIn / Google Scholar / Twitter
ORCID: 0000-0003-3037-3038 / Publons
Domain:
Animal cognition and behaviour / Associative learning
Research axis:
- Thalamocortical bases of adaptive behaviors
- Thalamic determinants of cognition
Scientific expertise:
- Integrated study of animal behaviour
- Circuit level analysis
- Functional anatomy
Projects:
- Neural bases of goal-directed behaviors
- Thalamic determinants of Schizophrenia Pathophysiology
- Ventral Midline Thalamus and Systems-Level Consolidation of Spatial Memories
Collaborations:
- Seralynne Vann, Cardiff university, Wales
- Alexander Groh, Heidelberg university, Germany
- John Dalrymple-Alford, Psychology Department, University of Canterbury, Christchurch, New Zealand
- Claire Rampon, Centre de Recherches sur la Cognition Animale, Université Paul Sabatier, Toulouse
- Jean-Christophe Cassel, Laboratoire d’Imagerie et de Neurosciences Cognitives, Université Louis Pasteur, Strasbourg
- Bruno Poucet, Laboratoire de Neurosciences Cognitives, Université de Provence
- Erik J Kremer, Institut de Génétique Moléculaire de Montpellier
Funding:
- Independent Investigator NARSAD Grant (2017-2019), 100k$, Thalamic determinants of Schizophrenia Pathophysiology
- ANR "THALAME" (2015-2019, 93k€, Partner),
- ANR "GOAL" (2015-2018, 160k€, Associated Researcher)
Selected publications:
- Alcaraz F, Fresno V, Marchand AR, Kremer EJ, Coutureau E, Wolff M. (2018)Thalamocortical and corticothalamic pathways differentially contribute to goal-directed behaviors in the rat.Elife. 2018 Feb 6;7. pii: e32517. doi: 10.7554/eLife.32517.
- Alcaraz F, Marchand AR, Courtand G, Coutureau E, Wolff M (2016) Parallel inputs from the mediodorsal thalamus to the prefrontal cortex in the rat. Eur J Neurosci 44:1972-1986.
- Alcaraz F, Marchand AR, Vidal E, Guillou A, Faugere A, Coutureau E, Wolff M (2015) Flexible Use of Predictive Cues beyond the Orbitofrontal Cortex: Role of the Submedius Thalamic Nucleus. J Neurosci 35:13183-13193.
- Wolff M, Alcaraz F, Marchand AR, Coutureau E (2015) Functional heterogeneity of the limbic thalamus: From hippocampal to cortical functions. Neurosci Biobehav Rev 54:120-130.
- Dalrymple-Alford JC, Harland B, Loukavenko EA, Perry B, Mercer S, Collings DA, Ulrich K, Abraham WC, McNaughton N, Wolff M (2015) Anterior thalamic nuclei lesions and recovery of function: Relevance to cognitive thalamus. Neurosci Biobehav Rev 54:145-160.
- Marchand A, Faugere A, Coutureau E, Wolff M (2014) A role for anterior thalamic nuclei in contextual fear memory. Brain Struct Funct 219:1575-1586.
- Dupire A, Kant P, Mons N, Marchand AR, Coutureau E, Dalrymple-Alford J, Wolff M (2013) A role for anterior thalamic nuclei in affective cognition: Interaction with environmental conditions. Hippocampus 23:392-404.
Publications 2006-2018:
2018
- Alcaraz F, Fresno V, Marchand AR, Kremer EJ, Coutureau E, Wolff M. (2018)Thalamocortical and corticothalamic pathways differentially contribute to goal-directed behaviors in the rat. Elife. 2018 Feb 6;7. pii: e32517. doi: 10.7554/eLife.32517.
2017
- Parkes SL, Ravassard PM, Cerpa JC, Wolff M, Ferreira G, Coutureau E.(2017) Insular and Ventrolateral Orbitofrontal Cortices Differentially Contribute to Goal-Directed Behavior in Rodents. Cereb Cortex. 1-13. doi: 10.1093/cercor/bhx132. [Epub ahead of print]
2016
- Alcaraz F, Marchand AR, Courtand G, Coutureau E, Wolff M (2016a) Parallel inputs from the mediodorsal thalamus to the prefrontal cortex in the rat. Eur J Neurosci 44:1972-1986.
- Alcaraz F, Naneix F, Desfosses E, Marchand AR, Wolff M*, Coutureau E* (2016b) Dissociable effects of anterior and mediodorsal thalamic lesions on spatial goal-directed behavior. Brain Struct Funct 221:79-89. * Contributed equally.
- Loukavenko EA*, Wolff M*, Poirier GL, Dalrymple-Alford JC (2016) Impaired spatial working memory after anterior thalamic lesions: recovery with cerebrolysin and enrichment. Brain Struct Funct 221:1955-1970. *Contributed equally.
2015
- Alcaraz F, Marchand AR, Vidal E, Guillou A, Faugere A, Coutureau E, Wolff M (2015) Flexible Use of Predictive Cues beyond the Orbitofrontal Cortex: Role of the Submedius Thalamic Nucleus. J Neurosci 35:13183-13193.
- Dalrymple-Alford JC, Harland B, Loukavenko EA, Perry B, Mercer S, Collings DA, Ulrich K, Abraham WC, McNaughton N, Wolff M (2015) Anterior thalamic nuclei lesions and recovery of function: Relevance to cognitive thalamus. Neurosci Biobehav Rev 54:145-160.
- Wolff M, Alcaraz F, Marchand AR, Coutureau E (2015a) Functional heterogeneity of the limbic thalamus: From hippocampal to cortical functions. Neurosci Biobehav Rev 54:120-130.
- Wolff M, Faugere A, Desfosses E, Coutureau E, Marchand AR (2015b) Mediodorsal but not anterior thalamic nuclei lesions impair acquisition of a conditional discrimination task. Neurobiol Learn Mem 125:80-84.
2014
- Marchand A, Faugere A, Coutureau E, Wolff M (2014) A role for anterior thalamic nuclei in contextual fear memory. Brain Struct Funct 219:1575-1586.
2013
- Dupire A, Kant P, Mons N, Marchand AR, Coutureau E, Dalrymple-Alford J, Wolff M (2013) A role for anterior thalamic nuclei in affective cognition: Interaction with environmental conditions. Hippocampus 23:392-404.
- Mendez-Lopez M, Arias JL, Bontempi B, Wolff M (2013) Reduced cytochrome oxidase activity in the retrosplenial cortex after lesions to the anterior thalamic nuclei. Behav Brain Res 250C:264-273.
- Moreau PH, Tsenkina Y, Lecourtier L, Lopez J, Cosquer B, Wolff M, Dalrymple-Alford J, Cassel JC (2013) Lesions of the anterior thalamic nuclei and intralaminar thalamic nuclei: place and visual discrimination learning in the water maze. Brain Struct Funct 218:657-667.
2006-2012
- Porte Y, Trifilieff P, Wolff M, Micheau J, Buhot MC, Mons N (2011) Extinction of spatial memory alters CREB phosphorylation in hippocampal CA1. Hippocampus 21:1169-1179.
- Segu L, Lecomte MJ, Wolff M, Santamaria J, Hen R, Dumuis A, Berrard S, Bockaert J, Buhot MC, Compan V (2010) Hyperfunction of muscarinic receptor maintains long-term memory in 5-HT4 receptor knock-out mice. PLoS One 5:e9529.
- Lopez J, Wolff M, Lecourtier L, Cosquer B, Bontempi B, Dalrymple-Alford J, Cassel JC (2009) The intralaminar thalamic nuclei contribute to remote spatial memory. J Neurosci 29:3302-3306.
- Will B, Dalrymple-Alford J, Wolff M, Cassel JC (2008a) Reflections on the use of the concept of plasticity in neurobiology. Translation and adaptation by Bruno Will, John Dalrymple-Alford, Mathieu Wolff and Jean-Christophe Cassel from J. Paillard, J Psychol 1976;1:33-47. Behav Brain Res 192:7-11.
- Will B, Dalrymple-Alford J, Wolff M, Cassel JC (2008b) The concept of brain plasticity—Paillard’s systemic analysis and emphasis on structure and function (followed by the translation of a seminal paper by Paillard on plasticity). Behav Brain Res 192:2-7.
- Wolff M, Gibb SJ, Cassel JC, Dalrymple-Alford JC (2008a) Anterior but not intralaminar thalamic nuclei support allocentric spatial memory. Neurobiol Learn Mem 90:71-80.
- Wolff M, Loukavenko EA, Will BE, Dalrymple-Alford JC (2008b) The extended hippocampal-diencephalic memory system: enriched housing promotes recovery of the flexible use of spatial representations after anterior thalamic lesions. Hippocampus 18:996-1007.
- Loukavenko EA, Ottley MC, Moran JP, Wolff M, Dalrymple-Alford JC (2007) Towards therapy to relieve memory impairment after anterior thalamic lesions: improved spatial working memory after immediate and delayed postoperative enrichment. Eur J Neurosci 26:3267-3276.
- Gibb SJ, Wolff M, Dalrymple-Alford JC (2006) Odour-place paired-associate learning and limbic thalamus: comparison of anterior, lateral and medial thalamic lesions. Behav Brain Res 172:155-168.
- Wolff M, Gibb SJ, Dalrymple-Alford JC (2006) Beyond spatial memory: the anterior thalamus and memory for the temporal order of a sequence of odor cues. J Neurosci 26:2907-2913.