Institut de Neurosciences Cognitives et Intégratives d'Aquitaine (UMR5287)

Aquitaine Institute for Cognitive and Integrative Neuroscience



INCIA - UMR 5287- CNRS
Université de Bordeaux

Zone nord Bat 2 2ème étage
146, rue Léo Saignat
33076 Bordeaux cedex
France

Téléphone 05.57.57.15.51
Télécopie 05.56.90.14.21

Supervisory authorities

CNRS Ecole Pratique des Hautes Etudes Université de Bordeaux

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Neurocampus Unitéde Formation de Biologie

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Allain Anne-Emilie

by Loïc Grattier - published on , updated on

Anne-Emilie Allain Ingeneer, CNRS

Contact: anne-emilie.allain@u-bordeaux1.fr

tel:+33 (0)5 40 00 25 68

Site : Carreire

Team:
Phycell

Domain:
Neurobiology of Development



Research axis:

  • development of spinal neural networks in mice embryo

Expertise:

  • neuron and organotypic cultures of the spinal cord of mouse embryos
  • calcium imaging
  • western blot
  • immunohistochemistry ; epifluorescence microscopy; confocal microscopy; pharmacology ; transgénic mouse

Projects:

  • development of spinal neural networks in mice embryo
  • analysis of the evolution of GABA/glycine inhibitory synapses to motoneurons
  • analysis of the role of the effects of modulatory descending pathways from cerebral trunk onto spinal cord neural networks maturation
  • role of Glycine in the maturation of spinal motor networks.

Publications 2006-2011:

  • Allain AE, Le Corronc H, Delpy A, Cazenave W, Meyrand P, Legendre P, Branchereau P. Maturation of the GABAergic transmission in normal and pathologic motoneurons. Neural Plast. 2011;2011:905624. 2011
  • Allain AE, Ségu L, Meyrand P, Branchereau P. Serotonin controls the maturation of the GABA phenotype in the ventral spinal cord via 5-HT receptors. Ann NY Acad Sci. 2010 Jan;1198(1):208-19. 2010
  • Scain AL, Le Corronc H, Allain AE, Muller E, Rigo JM, Meyrand P, Branchereau P, Legendre P. Glycine release from radial cells modulates the spontaneous activity and its propagation during early spinal cord development. J Neurosci. 2010 Jan 6;30(1):390-403. 2010
  • Delpy A, Allain AE, Meyrand P, Branchereau P. NKCC1 cotransporter inactivation underlies embryonic development of chloride-mediated inhibition in mouse spinal motoneuron. J Physiol. 2008 Feb 15;586(4):1059-75. 2008
  • Allain AE, Bairi A, Meyrand P, Branchereau P. Expression of the glycinergic system during the course of embryonic development in the mouse spinal cord and its co-localization with GABA immunoreactivity. J Comp Neurol. Apr 20;496(6):832-846. 2006
  • Allain AE, Meyrand P and Branchereau P. Ontogenic changes of the spinal GABAergic cell population are controlled by the serotonin (5-HT) system: implication of 5-HT1 receptor family. Journal of Neuroscience (2005) 25: 8714-8724.
  • Allain AE, Bairi A, Meyrand P, Branchereau P. Ontogenic changes of the GABAergic system in the embryonic mouse spinal cord. Brain Res. 2004 Mar 12;1000(1-2):134-47. 2004