Anne-Emilie Allain Ingeneer, CNRS
Contact: anne-emilie.allain@u-bordeaux1.fr
tel:+33 (0)5 40 00 25 68
Site : Carreire
Team:
Phycell
Domain:
Neurobiology of Development
Research axis:
- development of spinal neural networks in mice embryo
Expertise:
- neuron and organotypic cultures of the spinal cord of mouse embryos
- calcium imaging
- western blot
- immunohistochemistry ; epifluorescence microscopy; confocal microscopy; pharmacology ; transgénic mouse
Projects:
- development of spinal neural networks in mice embryo
- analysis of the evolution of GABA/glycine inhibitory synapses to motoneurons
- analysis of the role of the effects of modulatory descending pathways from cerebral trunk onto spinal cord neural networks maturation
- role of Glycine in the maturation of spinal motor networks.
Publications 2006-2011:
- Allain AE, Le Corronc H, Delpy A, Cazenave W, Meyrand P, Legendre P, Branchereau P. Maturation of the GABAergic transmission in normal and pathologic motoneurons. Neural Plast. 2011;2011:905624. 2011
- Allain AE, Ségu L, Meyrand P, Branchereau P. Serotonin controls the maturation of the GABA phenotype in the ventral spinal cord via 5-HT receptors. Ann NY Acad Sci. 2010 Jan;1198(1):208-19. 2010
- Scain AL, Le Corronc H, Allain AE, Muller E, Rigo JM, Meyrand P, Branchereau P, Legendre P. Glycine release from radial cells modulates the spontaneous activity and its propagation during early spinal cord development. J Neurosci. 2010 Jan 6;30(1):390-403. 2010
- Delpy A, Allain AE, Meyrand P, Branchereau P. NKCC1 cotransporter inactivation underlies embryonic development of chloride-mediated inhibition in mouse spinal motoneuron. J Physiol. 2008 Feb 15;586(4):1059-75. 2008
- Allain AE, Bairi A, Meyrand P, Branchereau P. Expression of the glycinergic system during the course of embryonic development in the mouse spinal cord and its co-localization with GABA immunoreactivity. J Comp Neurol. Apr 20;496(6):832-846. 2006
- Allain AE, Meyrand P and Branchereau P. Ontogenic changes of the spinal GABAergic cell population are controlled by the serotonin (5-HT) system: implication of 5-HT1 receptor family. Journal of Neuroscience (2005) 25: 8714-8724.
- Allain AE, Bairi A, Meyrand P, Branchereau P. Ontogenic changes of the GABAergic system in the embryonic mouse spinal cord. Brain Res. 2004 Mar 12;1000(1-2):134-47. 2004