Lionel Parra Iglesias 3D creation showing a schematic drawing of GABAA receptors and a GABAergic synaptic terminal (original 2D images from Maurice Garret).
Native GABAARs (top panel), which are heteropentameric structures containing α1, α2 or α3 with β and γ subunits, are located at the synapse (bottom panel) and mediate a phasic inhibitory effect. The aggregation of receptors on the postsynaptic domain depends on scaffolding proteins, including gephyrin. GABAARs containing the α5 or δ subunits are extra-synaptic with a high sensitivity to GABA and mediate tonic activity as a function of ambient transmitter level in the extracellular space. GABA levels depend on the expression of two isoforms of glutamate decarboxylase (GAD 67 and 65), the vesicular transporter VGAT, and the transporters GAT-1 and GAT-3.
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- Efficiency of Sensorimotor Networks: Posture and Gait in Young and Older Adults
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- Grégory Barrière and Jérôme Badaut, coordinators of a recently funded Era-Net Neuron international project
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- HYBRID team awarded a CNRS grant “Osez l’Interdisciplinarité” for interdisciplinary research with LABRI and INRIA Flowers teams.
- ImageJ-based automatic motion tracking in aquatic amphibian
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- Targeting Reciprocally Connected Brain Regions Through CAV-2 Mediated Interventions
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- Too Much Sugar During Adolescence May Alter Brain’s Reward Circuits
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- VOTE FOR GIULIA! A picture of an INCIA member has been selected to win at the AXA research fund photo context 2016!
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Welcome into the world of 3D design with Lionel Para Iglesias.
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