Lionel Parra Iglesias 3D creation showing a schematic drawing of GABAA receptors and a GABAergic synaptic terminal (original 2D images from Maurice Garret).
Native GABAARs (top panel), which are heteropentameric structures containing α1, α2 or α3 with β and γ subunits, are located at the synapse (bottom panel) and mediate a phasic inhibitory effect. The aggregation of receptors on the postsynaptic domain depends on scaffolding proteins, including gephyrin. GABAARs containing the α5 or δ subunits are extra-synaptic with a high sensitivity to GABA and mediate tonic activity as a function of ambient transmitter level in the extracellular space. GABA levels depend on the expression of two isoforms of glutamate decarboxylase (GAD 67 and 65), the vesicular transporter VGAT, and the transporters GAT-1 and GAT-3.
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- Efficiency of Sensorimotor Networks: Posture and Gait in Young and Older Adults
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- Grégory Barrière and Jérôme Badaut, coordinators of a recently funded Era-Net Neuron international project
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- HYBRID team awarded a CNRS grant “Osez l’Interdisciplinarité” for interdisciplinary research with LABRI and INRIA Flowers teams.
- HYBRID Team starting the ANR/DGA funded CoBioPro project, aiming to develop biomimetic controls for robotic arm and prosthesis.
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- Role of astrocyte aquaporin-4 in brain structure remodeling after traumatic brain injury: a combined MRI and STED microscopy study
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- Shoulder kinematics plus contextual target information enable control of multiple distal joints of a simulated prosthetic arm and hand
- Social harassment induces anxiety-like behaviour in crayfish by Julien Bacqué-Cazenave, Daniel Cattaert, Jean-Paul Delbecque* and Pascal Fossat*
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Welcome into the world of 3D design with Lionel Para Iglesias.
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