The goal of our research is to decipher the impact of the sensory-motor environment on both global motor physiology and possible development of motoneuronal pathologies. Using various animal models, including invertebrates, amphibians, rodents and humans that are complementary and offer specific opportunities, our research aims principally at understanding the fundamental processes of motoneuron development and motor function physiology in a context of permanent interaction between single neurons, neuronal networks and sensory information. Specific projects focusing on various developmental and motor pathologies (ALS, ASD, vestibulopathies) are also conducted.
Our technical expertise spans kinematics and motor behavior analyses, in vitro extracellular/intracellular electrophysiology and calcium imaging approaches, in vivo electromyography, neuropharmacology, as well as immunohistilogical, tracing and molecular techniques.
Team members
Sandrine Bertrand (DR2 CNRS) Pascal Branchereau (PR1 Univ. Bordeaux, HDR) Jean-René Cazalets (DR1 CNRS) William Cazenave (TCH Univ. Bordeaux) Denis Combes (PR1 Univ. Bordeaux, HDR) Antonny Czanecki (MCF Univ. Bordeaux) Etienne Guillaud (IR CNRS) Didier Le Ray (CRCN CNRS, HDR) Romuald Nargeot (MCF Univ. Bordeaux, HDR) Guy Simonnet (PREM Univ. Bordeaux)
Olena Bogdanova (Postdoctoral fellow, Fondation John Bost & Région Nouvelle-Aquitaine) Vincent Jecko (PhD student, Neurosurgeon) Léandre Lavenu (PhD student, GRP BRAIN2 "Inhibition project") Alexandre Maisterrrena (Assistant Engineer, ANR) Maelle Ollivier (PhD student, ANR) Alexandra Reichova (Postdoctoral fellow, AFM-Téléthon) Honmei Zhu (PhD student, Chinese Consulate)