DR CNRS
Contact:
serge.ahmed@u-bordeaux.fr
+33 (0)5 57 57 15 54
Site : Carreire
Team:
Choice, Addiction and Neurodysfunction
Social:
Twitter / LinkedIn / Google Scholar
Domain:
Addiction / Neuropsychopharmacology / Behavioral Neuroscience / Experimental Psychology
Research axis:
- Experimental study of addiction using an animal model approach
- Environmental, psychological, and neurobiological determinants of the hallmark stages and behavioral features of addiction, including: escalation of drug use which is a hallmark of the transition to addiction; individual drug preferences; loss of control under the influence; craving; and vulnerability to relapse
Scientific expertise:
- Operant and Pavlovian conditioning technologies
- Behavioral economics, choice and decision-making procedures
- PK/PD modeling of drug self-administration
- Conception, development, and validation of addiction models in animals
- Conceptual analysis of addiction theories
Projects:
- Psychological and neurobiological mechanisms involved in choice between drug and nondrug rewards
- Psychological and neurobiological mechanisms involved in loss of control under the drug influence
- Psychological and neurobiological mechanisms involved in drug intake escalation
Funding:
- CNRS / Université de Bordeaux
- INCa-IReSP (2023-2026), (PI), Validation d’un modèle animal de polyconsommation d’alcool et de cocaïne.
- ANR PRC (2020-2024), (PI), Cocaine users under the influence: processes and mechanisms.
Selected publications:
- Durand A, Girardeau P, Freese L, Ahmed SH (2022) Increased responsiveness to punishment of cocaine self-administration after experience with high punishment. Neurospsychopharmacoloy 47:444-453.
- George O, Ahmed SH, Gilpin NW (2022) Are We Compulsively Chasing Rainbows? Neuropsychopharmacology 47:2013-2015. All authors contributed equally.
- Vandaele Y, Augier E, Vouillac-Mendoza C, Ahmed SH (2022) Cocaine falls into oblivion during volitional initiation of choice trials. Addiction Biology 27 (6):e13235.
- Abarkan M, Fois G, Vouillac-Mendoza C, Ahmed SH, Guillem K. (2023) Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation. Neuropsychopharmacology ePub.
- Lenoir M, Navaille S, Vandaele Y, Vouillac-Mendoza C, Guillem K, Ahmed SH (2023) Large-scale brain correlates of sweet versus cocaine reward in rats. European Journal of Neuroscience ePub.