Institut de Neurosciences Cognitives et Intégratives d'Aquitaine (UMR5287)

Aquitaine Institute for Cognitive and Integrative Neuroscience



INCIA - UMR 5287- CNRS
Université de Bordeaux

Zone nord Bat 2 2ème étage
146, rue Léo Saignat
33076 Bordeaux cedex
France

Téléphone 05.57.57.15.51
Télécopie 05.56.90.14.21

Supervisory authorities

CNRS Ecole Pratique des Hautes Etudes Université de Bordeaux

Our partners

Neurocampus Unitéde Formation de Biologie

GDR

GDR Robotique GDR Mémoire GDR Multi-électrodes

Search




Home > Directory

Mons Nicole

by Vincent David - published on , updated on

Mons Nicole {JPEG}

Chargé de Recherches CNRS (CRHC), HDR

Contact
nicole.mons@u-bordeaux.fr
+33 (0)5 40 00 24 60

Site: Talence

Team: Decision and Adaptation

Social:
Publons / Google scholar

Domain:
Cognition and behaviour / Animal cognition and behaviour

Research axis:

  • Neural representation of emotional memories in the brain

Scientific expertise:

  • Molecular and epigenetic signatures of memory formation
  • Epigenetic alterations and glucocorticoid signaling in normal and pathological aging
  • Neural circuits

Projects:

  • Identifying the mechanisms by which neural circuits represent memories of aversive environmental contexts: how dynamic patterns of histone modifications underlie neuroadaptations to drug and/or fear.

Funding:

  • ANR PTSD MEMO (2014-2019, 30k€, Partner)
  • FRA (2015, 2016, 20k€, Associated researcher)

Selected Publications:

- Porte Y, Trifilieff P, Wolff M, Micheau J, Buhot MC, Mons N (2011) Extinction of spatial memory
alters CREB phosphorylation in hippocampal CA1. Hippocampus.
- Porte Y, Buhot MC, Mons N (2008) Alteration of CREB phosphorylation and spatial memory deficits in aged 129T2/Sv mice. Neurobiol Aging 29:1533-1546.
- Herry ,C, Mons, N (2004) Resistance to extinction is associated with impaired immediate early gene induction in medial prefrontal cortex and amygdala. Eur J Neurosci. 20:781-790.
- Herry C, Trifilieff P, Micheau J and Mons N (2006) Extinction of auditory fear conditioning requires MAPK/ERK activation in the basolateral amygdala. Eur J Neurosci 24:261-269.
- Mons N, Premont RT, Dubourg P, Harry A, Iyengar R and Cooper DMF (1995) Immunohistochemical localization of adenylyl cyclase in rat brain indicates a highly selective concentration at synapses. Proc Natl Acad Sci. 92:8473-8477

Other publications:
- Porte Y, Trifilieff P, Wolff M, Micheau J, Buhot MC, Mons N (2011) Extinction of spatial memory
alters CREB phosphorylation in hippocampal CA1. Hippocampus.
- Boucard A, Mons N, Micheau J, Nogues X (2009) Activating a memory system focuses connectivity toward its central structure. Behav Brain Res 204:226-234
- Boucher AA, Vivier L, Metna-Laurent M, Brayda-Bruno L, Mons N, Arnold JC, Micheau J (2009) Chronic treatment with Delta(9)-tetrahydrocannabinol impairs spatial memory and reduces zif268 expression in the mouse forebrain. Behav Pharmacol 20:45-55.
- Mingaud F, Mormede C, Etchamendy N, Mons N, Niedergang B, Wietrzych M, Pallet V, Jaffard R, Krezel W, Higueret P, Marighetto A (2008) Retinoid hyposignaling contributes to aging-related decline in hippocampal function in short-term/working memory organization and long-term declarative memory encoding in mice. J Neurosci 28:279-291.
- Porte Y, Buhot MC, Mons N (2008) Alteration of CREB phosphorylation and spatial memory deficits in aged 129T2/Sv mice. Neurobiol Aging 29:1533-1546.
- Porte Y, Buhot MC, Mons N (2008) Spatial memory in the Morris water maze and activation of cyclic AMP response element binding (CREB) protein within the mouse hippocampus. Learn Mem 15:885-894.
- Trifilieff P, Calandreau L, Herry C, Mons N, Micheau J (2007) Biphasic ERK1/2 activation in both the hippocampus and amygdala may reveal a system consolidation of contextual fear memory. Neurobiol Learn Mem 88:424-434.
- Martel G, Blanchard J, Mons N, Gastambide F, Micheau J, Guillou JL (2007) Dynamic interplays between memory systems depend on practice: The hippocampus is not always the first to provide solution. Neuroscience 150:743-753.
- Piérard C, Liscia P, Philippin JN, Mons N, Lafon T, Chauveau F, Van Beers P, Drouet I, Serra A, Jouanin JC, Béracochéa D (2007) Modafinil restores memory performance and neural activity impaired by sleep deprivation in mice. Pharmacol Biochem Behav 88:55-63.
- Herry C, Trifilieff P, Micheau J and Mons N (2006) Extinction of auditory fear conditioning requires MAPK/ERK activation in the basolateral amygdala. Eur J Neurosci 24:261-269
- Florian C, Mons N and Roullet P (2006) CREB Antisense Oligodeoxynucleotide Administration into the Dorsal Hippocampal CA3-Region Impairs Long- but not Short-Term Spatial Memory in Mice. Learn Mem 13:465-472.
- Calandreau L, Trifilieff P, Mons N, Costes L, Marien M, Marighetto A, Micheau J, Jaffard R, Desmedt A (2006) Extracellular hippocampal acetylcholine level controls amygdala function and promotes adaptive conditioned emotional response. J Neurosci 26:13556-13566.
- Trifilieff P, Herry C, Vanhoutte P, Caboche J, Desmedt A, Mons N, Micheau J (2006) Contextual fear memory consolidation requires two independent phases of hippocampal ERK/CREB activation. Learn Mem 13:349-358.