Professeur PhD, Université de Bordeaux
Contact:
jean.louis.guillou@u-bordeaux.fr
+33 (0)5 40 00 89 21
Site : Talence
Team:
Emotion, Motivation, Cognition (EMOTIV)
Domain:
Cognition and behaviour / Animal cognition and behaviour
Research axis:
- Brain and molecular mechanisms of interactions between memory systems
- Roles of positive and negative emotional feedbacks on memory formation
- Cerebral somatostatin networks and their functions
Scientific expertise:
- Integrated studies of animal behaviour
- Behavioural pharmacology
Projects:
- Impact of emotional events in developing memory pathology
- Roles of somatostatin and somatostatin receptor subtypes in emotion and cognition: relationships with aging disorders
Collaborations:
- Jacques Epelbaum, Center for Psychiatry & Neuroscience, Université Paris Descartes, Sorbonne, Paris
- Cécile Viollet, Center for Psychiatry & Neuroscience, Université Paris Descartes, Sorbonne, Paris
- Catherine Loudes
- Daniel Hoyer
Grants:
- B2V Observatory of Memories PhD Grant
- Programme interdisciplinaire CNRS: longévité et viellissement
Selected Publications:
- Nicolay-Kritter K, Lassalle J, Guillou JL, Mons N. (2021) The histone H3 lysine 9 methyltransferase G9a/GLP complex activity is required for long-term consolidation of spatial memory in mice. Neurobiol Learn Mem. 2021 Mar;179:107406
- Prévôt TD, Viollet C, Epelbaum J, Dominguez G, Béracochéa D, Guillou JL (2019) sst2-receptor gene deletion exacerbates chronic stress-induced deficits: Consequences for emotional and cognitive ageing. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Aug 30;86:390-400.
- Dominguez G, Henkous N, Prevot T, David V, Guillou JL, Belzung C, Mons N, Béracochéa D (2019) Sustained corticosterone rise in the prefrontal cortex is a key factor for chronic stress-induced working memory deficits in mice. Neurobiol Stress. 2019 Apr 4;10:100161.
- Prévôt TD, Gastambide F, Viollet C, Henkous N, Martel G, Epelbaum J, Béracochéa D, Guillou JL (2017) Roles of Hippocampal Somatostatin Receptor Subtypes in Stress Response and Emotionality. Neuropsychopharmacology. 2017 Jul;42(8):1647-1656.
- Baudonnat M, Guillou JL, Husson M, Bohbot VD, Schwabe L, David V (2017) Morphine Reward Promotes Cue-Sensitive Learning: Implication of Dorsal Striatal CREB Activity. Front Psychiatry. 2017 May 30;8:87.
- Prévôt TD, Gastambide F, Viollet C, Henkous N, Martel G, Epelbaum J, Béracochéa D, Guillou JL (2017) Roles of Hippocampal Somatostatin Receptor Subtypes in Stress Response and Emotionality. Neuropsychopharmacology. 2017 Jul;42(8):1647-1656.
- Dagnas M, Guillou JL, Prévôt T, Mons (2013) HDAC inhibition facilitates the switch between memory systems in young but not aged mice. J Neurosci. 2013 Jan 30;33(5):1954-63.
- Gastambide F, Lepousez G, Viollet C, Loudes C, Epelbaum J, Guillou JL (2010) Cooperation between hippocampal somatostatin receptor subtypes 4 and 2: functional relevance in interactive memory systems. Hippocampus 20:745-757.
- Martel G, Jaffard R, Guillou JL (2010) Identification of hippocampus-dependent and hippocampus independent memory components in step-down inhibitory avoidance tasks. Behav Brain Res 207:138-143.
- Epelbaum J, Guillou JL, Gastambide F, Hoyer D, Duron E, Viollet C (2009) Somatostatin, Alzheimer’s disease and cognition: an old story coming of age? Prog Neurobiol 89:153-161.
- Gastambide F, Viollet C, Lepousez G, Epelbaum J, Guillou JL (2009) Hippocampal SSTR4 somatostatin receptors control the selection of memory strategies. Psychopharmacology (Berl) 202:153-163.
- Blanchard J, Martel G, Guillou JL, Nogues X, Micheau J (2008) Impairment of spatial memory consolidation in APP(751SL) mice results in cue-guided response. Neurobiol Aging 29:1011-1021.
- Martel G, Blanchard J, Mons N, Gastambide F, Micheau J, Guillou JL (2007) Dynamic interplays between memory systems depend on practice: the hippocampus is not always the first to provide solution. Neuroscience 150:743-753.
- Martel G, Millard A, Jaffard R, Guillou JL (2006) Stimulation of hippocampal adenylyl cyclase activity dissociates memory consolidation processes for response and place learning. Learn Mem 13:342-348.